Endocrine Abstracts

The endogenous growth hormone secretagogue (GHS), ghrelin, is an important regulator of energy homeostasis. Peripheral and central administration of ghrelin increase food intake, body weight and fat mass, effects which are mediated by the growth hormone secretagogue receptor type 1a (GHS-R 1a). Although the central actions of ghrelin on adiposity have been extensively studied, the direct peripheral effects of ghrelin on adipose tissue remain poorly understood. This study aimed...